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Thesis Details
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Title
Certificate
Declaration
Dedication
Acknowledgement
Abstract
Preface
Table of Contents
List of Figures
List of Tables
Abbreviations
1. Review of literature
1.1. Cancer statistics
1.2. Acquired functional capabilities of cancer cells
1.3.Tthe characteristics of cancer cells
1.4.M molecular basis of cancer
1.5. Apoptosis and cancer
1.6. Reactive oxygen species and cancer
1.7. Cancer therapy
1.8. Inflammation and cancer
1.9. Plant derived anticancer agents
1.10. Importance of biotechnology in the propagation of medicinal plants
1.11. Dasamoola
2. Materials and Methods
2.2.1. Preparation of extract
2.2.2. Micro propagation
2.2.3. Determination of in vitro antioxidant activity
2.2.4. Determination of anti inflammatory activities
2.2.5. Short-term cytotoxic activity
2.2.6. Biochemical analysis
2.2.7. Histopathology
3. Micropropagation of Solanum xanthocarpum and Tribulus terrestris and comparison of their chemical profile with ex vitro plants
3 1. Micropropagation of Solanum xanthocarpum and Tribulus terrestris
3.1.1. Micropropagation of Solanum xanthocarpum
3.1.2. Micropropagation of Tribulus terrestris
3.2. Phytochemical screening of ex vitro and in vitro propagated plants of Solanum xanthocarpum and Tribulus terrestris
4. Anticancer activities of Solanum xanthocarpum and Tribulus terrestris
4.1. Anti oxidant activity of Solanum xanthocarpum and Tribulus terrestris and their comparison with micropropagated plants
4.2. Anti inflammatory activity of Solanum xanthocarpum and Tribulus terrestris
4.3. Cytotoxicity of Solanum xanthocarpum and Tribulus terrestris and their comparison with micropropagated plants
4.4. Anti tumor activity of Solanum xanthocarpum and Tribulus terrestris
5. Mechanism of anti cancer activities of Solanum xanthocarpum and Tribulus terrestris
6. Protective activities of Solanum xanthocarpum and Tribulus terrestris
6.1. Gastroprotective activities of Solanum xanthocarpum and Tribulus terrestris
6.2. Protective effect of Solanum xanthocarpum and Tribulus terrestris on cisplatin induced nephrotoxicity
6.3. Protective activityof Solanum xanthocarpum and Tribulus terrestris against doxorubicin induced cardiotoxicity, nephrotoxicity and hepatotoxicity
7. Summary and Conclusions
Bibliography