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  • TITLE -1
  • TITLE-2
  • DEDICATION
  • DECLARATION
  • CERTIFICATE
  • ACKNOWLEDGEMENT
  • PREFACE
  • ABSTRACT
  • CONTENTS
  • LIST OF TABLES
  • LIST OF FIGURES
  • 1. GENERAL INTRODUCTION
  • 2. ENDOSULPHAN - GENERAL ACCOUNTAND LITERATURE REVIEW
  • 2.1 Endosulphan
  • 2.2 Molecular formula: C9H6Cl6O3S
  • 2.3 Relative Molecular Mass: 406.9
  • 2.4 Chemical Name
  • 2.5 Molecular Structure
  • 2.6. Physical and Chemical Properties
  • 2.7. Toxicity Classification
  • 2.8 Reports of Endosulphan Poisoning Around the World
  • 2.9 Literature Review
  • Fig: 2.2. Chemical degradation of endosulphan in the environment
  • 2.10 Effects on human health
  • 3. MATERIALS AND METHODS
  • 3.1 Experimental Animals
  • 3.2 Experimental Design
  • 3.3 Biochemcal Studies
  • 3.4 Histopathological Studies: (Varley, 1980)
  • 3.5 Residue Analysis
  • 4. OBSERVATIONS AND RESULTS
  • 4.1. Clinical Symptoms / Morphological / Behavioural Changes
  • 4.2 Effect on body weight and food intake
  • 4.3 Biochemical Estimations
  • 4.4 Histopathological Findings
  • 4.5 Residue Analysis
  • 5. DISCUSSION
  • 5.1 Glycogen
  • 5.2 Total Protein
  • 5.3 Lipid
  • 5.4 Alkaline and Acid Phosphatase (ALK and ACP)
  • 5.5 Total Adenosine Triphosphatase (Total ATPase)
  • 5.6 Lactic Dehydrogenase and Succinic Dehydrogenase (LDH & SDH)
  • 5.7 Acetyle Cholinesterase (Ach E)
  • 5.8 Histopathology
  • 5.9 Residual Metabolites
  • 6. SUMMARY AND CONCLUSIONS
  • 6.1 Summary
  • 6.2 Conclusion
  • 6.3 Recommendations
  • REFERENCE
  • APPENDIX
  • Plate 1
  • Plate 2
  • Plate 3
  • Plate 4
  • Plate 5
  • Plate 6
  • Table 1
  • Table2
  • Table 3
  • Table4
  • Table5
  • Table 6
  • Table 7
  • Table 8
  • Table 9
  • Table 10
  • Table 11
  • Table 12
  • Table 13
  • Table 14
  • Table 15
  • Table 16
  • Table17
  • Table18
  • Table 19
  • Table 20
  • Table 21
  • Table 22
  • Table 23
  • Table 24
  • Table 25
  • Table 26
  • Table 27
  • Table28
  • Table29
  • Table 30
  • Table 31
  • Table 32
  • Table 33
  • Table 34
  • Table 35
  • Table36
  • Table 37
  • Table38
  • Table39
  • Table 40
  • Fig. 4.1
  • Fig. 4.2
  • Fig. 4.3
  • Fig. 4.4
  • Fig. 4.5
  • Fig. 4.6
  • Fig. 4.7
  • Fig. 4.8
  • Fig. 4.9
  • Fig. 4.10
  • Fig. 4.11
  • Fig. 4.12
  • Fig. 4.13
  • Fig. 4.14
  • Fig. 4.15
  • Fig. 4.16
  • Fig. 4.17
  • Fig. 4.18
  • Fig. 4.19
  • Fig. 4.20
  • Fig. 4.21
  • Fig. 4.22
  • Fig. 4.23
  • Fig. 4.24
  • Fig. 4.2 5
  • Fig. 4.2 7
  • Fig. 4.27
  • Fig. 4.28
  • Fig. 4.29
  • Fig. 4.30
  • Fig. 4.31
  • Plate 1
  • Plate 2
  • Plate 3
  • Plate 4
  • Plate 5
  • Plate 6
  • List of abbreviation
  • List of Publication
  • A biochemical study on the effect of thiodan on the common indian frog euphlyctis hexadactylus
  • Impact on thiodan membrane bound enzyme alkaline phosphatase in liver and blood of albino mice