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Full Screen- Title
- CERTIFICATE-1
- CERTIFICATE-2
- DECLARATION
- ACKNOWLEDGEMENT
- CONTENTS
- ABBREVIATIONS
- 1. Introduction
- 1.1 Liver and xenobiotic metabolism
- 1.2 Hepatotoxins and their effect
- 1.2.1 Direct hepatotoxins
- 1.2.2 Indirect hepatotoxins
- 1.3 Carbon tetrachloride as a hepatotoxin
- 1.4 Types of hepatic diseases (Ram and Goel, 1999)
- 1.5 Management of Hepatic diseases
- 1.6 Aims and objectives of the study
- 2. Review of Literature
- 2.1 Hepatoprotection
- 2.2 Antihepatotoxic medicinal plants
- 2.3 Present scenario of the selected medicinal plants
- 2.4 Antihepatotoxic herbal formulations
- 2.5 Kamilari as a hepatoprotective drug
- 3. Materials and Methods
- 3.1 Animals
- 3.2 Plant materials / polyherbal formulation and chemicals
- 3.3 Experimental design
- 4. Effect of Kamilari and selected Medicinal Plants on CCI4-induced Hepatotoxicity in rats
- 4.1 Introduction
- 4.2 Materials and Methods
- 4.3 Results and Discussion
- 4.3.1 Changes in the activities of serum enzymes
- 4.3.2 Changes in the level of bilirubin and protein in serum
- 4.3.3 Changes in the levels of serum and tissue total lipids, cholesterol, phospholipids and triglycerides
- 5. Antiperoxidative effect of G.Glabra and W.Fruticosa
- 5.1 Introduction
- 5.2 Materials and Methods
- 5.3 Results and discussion
- 5.3.1 Changes in the level of lipid peroxides
- 5.3.2 Changes in the antioxidant status
- 6. Histopathological study of Liver
- 6.1 Introduction
- 6.2 Materials and Methods
- 6.3 Results and Discussion
- Table 6.1 Histopathological changes of liver
- Fig. 6.3.1 Photomicrographs of liver section
- Fig. 6.3.2 Photomicrographs of liver section taken from CC14:
- Fig.6.3.3 Photomimgraphs of liver section taken from CC14
- 7. General Discussion
- Significance of the present investigation
- 8. Summary
- References