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Full Screen- Title
- Declaration
- Certificate
- Dedication
- Acknowledgement
- Contents
- Abstract
- Preface
- List of Tables
- List of Figures
- Abbreviations
- 1. Introduction and review of literature
- 1.2. How does radiation interact with cells
- 1.3. The role of ROS in normal physiology
- 1.4. Effects of radiation on biological system
- 1.5. Cellular defense mechanisms against radiation-induced oxidative stress
- 1.6. Necessity of radioprotecting agents
- 1.7. Radiomodulators: definition and types
- 1.8. Radioprotective drug development initiatives
- 1.9. Antioxidants as radioprotectors
- 1.10. Ascorbic acid (Vitamin c)
- 1.11. As AG (Ascorbic acid-2-glucoside)
- 2. Materials and Methods
- 3. Free radical scavenging and anti-inflammatory activities of Ascorbic acid-2 glucoside
- 4. Tissue protective efficacy of Ascorbic acid-2 glucoside against γ-radiation-induced damages in mice
- 5. Radio protection by Ascorbic acid-2-Glucoside at the molecular level: Protection of membrane lipids and DNA against γ-radiation
- 6. Radio protection by Ascorbic acid 2-Glucose assessed by cytogenetics parameters
- 7. Enhancement in repair of radiation-induced DNA strand breaks by Ascorbic acid-2 Glucoside
- 8. Amelioration of side effects of cancer chemotherapeutic drug, Cisplatin, by Ascorbic acid-2 Glucoside in mice
- 9. Studies on the use of Ascorbic acid 2- Glucoside as an adjuvant in radiotherapy in mouse model
- Summary and Conclusion
- Bibliography