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  • TITLE
  • DECLARATION
  • CERTIFICATE
  • ACKNOWLEDGEMENT
  • TABLE OF CONTENTS
  • ABSTRACT
  • PREFACE
  • LIST OF TABLES
  • LIST OF FIGURES
  • LIST OF ABBREVIATIONS
  • 1. REVIEW OF LITERATURE
  • Table of contents
  • 1.1. Introduction
  • 1.2. Hallmarks of cancer cell
  • 1.3. Concept of carcinogenesis
  • 1.4. Cellular and molecular mechanisms of multistage carcinogenesis
  • 1.5. Role of oncogenes and tumor suppressor genes
  • 1.6. Apoptosis: A program for cell death
  • 1.7. Viral carcinogenesis
  • 1.8. Concept of radioprotectors and chemoprotectors as adjuvant in cancer therapy
  • 1.9. Chemoprevention
  • 1.10. Scope of the present study
  • 2. MATERIALS AND METHODS
  • Table of contents
  • 2.1. Materials
  • 2.2. Methods
  • 2.3. Statistical Analysis
  • 3. ANTIVIRAL ACTIVITY OF PHYLLANTHUS AMARUS, BERBERINE, CURCUMIN AND PICROLIV
  • Table of contents
  • 3.1. Introduction
  • 3.2. Materials and Methods
  • 3.3. Results
  • 3.4. Discussion
  • 4. INHIBITION OF FRIEND VIRUS INDUCED ERYTHROLEUKEMIA IN MICE BY PHYLLANTHUS AMARUS, BERBERINE, CURCUMIN AND PICROLIV
  • Table of contents
  • 4.1. Introduction
  • 4.2. Materials and Methods
  • 4.3. Results
  • 4.4. Discussion
  • 5. INDUCTION OF APOPTOSIS BY PHYLLANTHUS AMARUS WITH POSSIBLE MECHANISM OF ACTION
  • Table of contents
  • 5.1. Introduction
  • 5.2. Materials and Methods
  • 5.3. Results
  • 5.4. Discussion
  • 6. AMELIORATION OF RADIOTHERAPY AND CHEMOTHERAPY ASSOCIATED TOXICITIES BY PHYLLANTHUS AMARUS IN MICE
  • Table of contents
  • 6.1. Introduction
  • 6.2. Materials and Methods
  • 6.3. Results
  • 6.4. Discussion
  • 7. EFFECT OF PHYLLANTHUS AMARUS ON DRUG METABOLIZING ENZYMES
  • Table of contents
  • 7.1. Introduction
  • 7.2. Materials and Methods
  • 7.3. Results
  • 7.4. Discussion
  • SUMMARY AND CONCLUSION
  • BIBLIOGRAPHY
  • LIST OF PUBLICATIONS