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  • Title
  • Dedication
  • Declaration
  • Certificate
  • Acknowledgement
  • Abstract
  • Contents
  • List of Abbreviations
  • 1. Context of the thesis
  • 2. A review on chiral pyrrolidines based natural products and their synthetic protocol
  • 3. Molecular structure determination of dimethyl (2S, 3S) and (2S, 3R) tetrahydro-3 hydroxy-5-oxo-2, 3-furandicarboxylate using different chiroptical spectroscopic method
  • 4. Synthesis of enantiopure 3-substituted and 3,4-disubstituted pyrrolidinediones and determination of molecular structure
  • 5. Synthesis pf crispine analogue from (2S,3S)- tetrahydro-3-hydroxy-5-oxo-3,3-furandicarboxylic acid and evaluation of biological activity
  • 6. Attempted synthesis of bioactive molecules using (6aS0-2,4,6-trioxotetrahydrofuro [3,4-b]furan-3(4H)-yl acetate
  • Summary and Conclusion
  • Bibliography
  • List of publications