Online Thesis Search Results

Title
DEDICATION
CERTIFICATE
DECLARATION
ACKNOWLEDGEMENT
CONTENTS
ABSTRACT
1. CHIRAL HYDROXY COMPOUNDS AS LIGANDS IN ASYMMETRIC SYNTHESIS
1.1 Introduction
1.2 Chiral alcohols as ligands in asymmetric synthesis
1.2.1 Chiral 1, 2 and 1, 3 diols
1.2.2 Chiral 1, 4-diols
(a) Catalytic asymmetric Diels-Alder reaction
(b) Asymmetric[2+2] cycloaddition reaction
(c) Asymmetric intramolecular ene reaction
(d) Asymmetric hydrocyanation of aldehydes
(e) Addition of Grignard reagents to ketones
(f) Addition of dialkylzinc to aldehydes
(g) Hydrosilylation of aromatic ketones
(h) Non reductive enantioselective ring opening
(i) Michael additions
(j) Optical resolutions
1.3 Conclusions
2. SCOPE AND ORCANISATION OF THE THESIS
3. SYNTHETIC INVESTIGATIONS ON (2s, 3s) -TETRAHYDRO-3 -HYDROXY-5-OXO-2, 3 -FURANDICARBOXYLIC ACID
III.1 Introduction
III.2 Results and Discussion
III.2. Structural analysis of (2S, 3S) and (2S, 3R) -Tetrahydro-3-hydroxy-5-0x0-2, 3-fiLrandicarboxyliacci ds
III.2.2 Attempts towards the synthesis of chiral moleculescontaining y-butyroladone moiety from (2S73S) -Tetrahydr0-3-hydtoxy-5-0~0-2, 3-fudricaanr boxylic acid
III.3 General Experimental Details
III.4 Experimental
4. SYNTHESIS OF (4S, 5S) -4- (2-HYDROXY-2, 2-DlARYL ETHYL) -2, 2-DIMETHYL-α, α, α, α -TETRA ARYL-1, 3-DIOXOLANE-4, 5-DIMETHANOLS AND THEIR CATALYTIC STUDlES
IV.l Introduction
IV.1.1 Chiral Hydroxy Compounds used as Iigands or chiralprecursors in Asymmetric Synthesis
IV. 1.2 Asymmetric Diels-Alder Reactions
IV.2 Results and discussion
IV.2.1 Preparation of Trimethyl Ester and Ketal from Garcinia acid
IV.2.2 Preparation of (4S, 5S) -4- (2-hydroxy-2, 2-diareytlh yl) -2, 2-dimethyl-α, α, α, α-tetraaryl, 1, 3 dioxolane -4, 5-dimethanols
IV.2.3 Asymmetric Diels-Alder reaction employing (45, 5s) -4- (2-hydroxy-2, 2-diaryI ethyl) -2, 2-dimethyl -α, α, α, α-tetraaryl-1, 3-dioxolane-4, 5-dimethanoals as chiral ligands
IV.3 Experimental
5. SUMMARY OF THE THESIS
REFERENCES
Publications / Patents