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Title
DECLARATION
CERTIFICATE
CONTENTS
ACKNOWLEDGEMENT
List of symbols and Abbreviations
CHAPTER - I
I - I Introduction
I - II Objectives
I - III Review of Literature
I - IV Methodology
Modified diet &Life Style Test to measure Total C
Modified diet
Modified lifestyle
Test to measure Total Cholesterol
Carr - Drekter method
Test to measure High Density Lipoprotein
Test to measure Tryglycerides
Blood pressure
Electrocardiogram Tread mill test
Treadmill test
I -V Results
Statistical analysis
Table I: - Comparison of lipid profile levels of healthy subjectsand diseased subjects
Table II: - Changes in the lipid profile level of intervention group.
Table III: - Changes in the lipid profile level in the control group.
Graph I Differences in the serum lipid profile of CAD patientsand Subjects free of CAD
Graph II: Changes in the serum Total cholesterol level in theIntervention group and control group.
Graph III Changes in the serum HDL level in theIntervention group and control group.
Graph IV: Changes in the serum LDL level in theIntervention group and control group.
Graph V: Changes in the serum VLDL level in theIntervention group and control group.
Graph VI: Changes in the serum Triglyceride level in theIntervention group and control group.
Graph VII Changes in Systolic Pressure through an Intervalof 3 months each
Graph VIII Changes in a diastolic pressure through an lntervalChanges in Diastolic Pressure through an lnterval of3 months each
I -VI Discussion
I - VII Conclusion
CHAPTER II
II - I Introduction
II - II Objectives
II - III Review of literature
II - IV Methodology
Rabbit feed
Ingredients of Mineral Mixture
CONTENTS of Polybion
Feeding Design
Statistical Analysis
Collection of blood samples
Histological studies
Composition of 10% buffered formaline
Automatic orocessing
1. Harriss haematoxylin preparation
2. Eosin Preparation
Procedure for staining.
II -V Results
Plate 1 Light Micrograph demonstrating cross sections of aorta of control with normal intima, media and adventitia. (10X)
Plate 2 Light Micrograph demonstrating cross sections of aorta ofcontrol group with normal intima., m.e dia and adventitia. (40X)
Plate 3 Light Micrograph demonstrating cross sections of aorta of cholesterol group exhibiting SMC proliferation in the intima. (4X)
Plate 4 Light Micrograph demonstrating cross sections of aorta of cholesterol group exhibiting SMC proliferation in the intima. (10X)
Plate 5 Light Micrograph demonstrating cross sections of aorta of cholesterol group exhibiting SMC proliferation in the intima. (40X)
Plate 6 Light Micrograph demonstmting the fatty streak
Plate 7 Light Micrograph demonstrating foam cell formation in the intima of cholesterol group (10X)
Plate 8 Light Micrograph demonstrating foam cell formation in the intima of cholesterol group. (40X)
Plate 9 Light Micrograpn demonstrating cross sections of aorta ofcoconut oil group exhibiting slight thickening in tbe intirna. (4X)
Plate 10 Light Micrograph demostrating cross sections of aorta of cocunut oil group exhibiting slight thickening in the intima. (l0X)
Plate 11 Light Micrograph demostrating cross sections of aorta of cocunut oil group exhibiting form cell formation in the intima. (4X)
Plate 12 Light Micrograph demostrating cross sections of aorta of cocunut oil group exhibiting form cell formation in the intima. (10X)
Plate 13 Light Micrograph demonstrating cross sections of aorta sfcoconut oil>group exhibiting form cell formation in the intirna. (lOX)
Plate 14 Light Micrograph demonstrating cross sections of aorta ofcoconut oil group exhibiting foam cell formation in the intima. (40X)
Plate 15 Light Micrograph demonstrating normal coronary arteries of control group (40X) .. . .. .-, .- . . .. - .. ., --.. .. .-., cotmug. arteries ofcootd geup (40x1
Plate 16 Light Micrograph demonstrating slight thickening in the coronary arteries of cholesterol group. (4X)
Plate 17 Light Micrograph demonstrating slight thickening in the coronary arteries of cholesterol group. (10X)
Plate 18 Light Micrograph demonstrating slight thickening in the coronary arteries of cholesterol group. (40X)
Plate 19 Light Micrograph demonstrating slight thickening in the coronary arteries of cholesterol group. (10X)
Plate 20 Light Micrograph demonstrating slight thickening in the coronary arteries of cholesterol group. (40X)
Plate 21 Light Micrograph demonstrating normal coronary arteries of coconut oil group. (l0X)
Plate 22 Light Micrograph demonstrating normal coronary arteries of coconut oil group. (40X)
Plate 23 Light Micrograph demonstrating normal liver cells (C.S) of control group (10X)
Plate 24 Light Micrograph demonstrating normal liver cells (C.S) of control group (40X)
Plate 25 Light Micrograph demonstrating normal liver cells (C-S) of cholesterol group (10x)
Plate 26 Light Micrograph demonstrating normalliver cells (C, S) of cholesterol group (40X)
Plate 27 Light Micrograph demonstrating normal liver cells (C.S) of coconut oil group (10X)
Plate 28 Light Micrograph demonstrating normal liver cells (C.S) of coconut oil group (40X)
II -VI Discussion
Serum Total Cholesterol
Serum HDL Cholesterol
Serum Triglycerides
Serum LDL cholesterol
Serum VLDL cholesterol
II -VII Conclusion
III Summary
References