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Full Screen- Title
- Declaration
- Certificate
- Acknowledgement
- Dedication
- Abstract
- Preface
- Contents
- List of Tables
- List of Figures
- Abbreviations
- 1. Review of Literature
- 1.2. Natural products as source of medicine
- 1.3. Plant secondary metabolites
- 1.4. Natural compounds as chemotherapeutic agents
- 1.5. Discoveries of cytotoxic phytochemicals
- 1.6. Camptothecin
- 1.7. 10-hydroxy camptothecin
- 1.9. Production of Secondary Metabolites by Plant Cell Cultures
- 1.10. Strategies to increase secondary metabolite production in plant cell Cultures
- 1.11. Genetic manipulation of medicinal plants
- 1.12. Metabolic engineering
- 1.13. The genus Ophiorrhiza
- 1.14. Camptothecin production by tissue culture
- 2. Materials and Methods
- 3. Identification and Quantification of Camptothecin and 10-Hydroxy camptothecin from Ophiorrhiza eriantha
- 4. Regeneration of Ophiorrhiza eriantha
- 5. Camptothecin and 10-hydroxy camptothecin production from in vitro cultures of Ophiorrhiza erianth
- 6. Enhancement of Camptothecin and 10-Hydroxy camptothecin in Cell Cultures of Ophiorrhiza eriantha with Elicitors
- 7. Precursor feeding on the production of Camptothecin and 10-hydroxy Camptothecin in Ophiorrhiza eriantha
- 8. Permeabilization of camptothecin and 10-hydroxy camptothecin from Ophiorrhiza eriantha
- 9. Antioxidant Enzyme Activities of Ophiorrhiza eriantha Cultures Under Radiation Induced Stress
- 10. RAPD Analysis of Callus Derived plant of Ophiorrhiza eriantha and its Mother plant
- 11. Summary and Conclusion
- Bibliography